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These could include pancreatitis, gallbladder disease, and even kidney injury

While both medications can be effective in their respective roles, their combined use necessitates a thorough understanding of each drug's pharmacodynamics and potential side effects

When people talk about GLP-1 medications, they are referring to drugs that mimic the effects of glucagon-like peptide-1 (GLP-1), a hormone the body naturally releases after eating

Since muscle burns roughly 6 calories per pound daily at rest compared to 2 calories for fat, losing that muscle reduces your daily burn by 40 to 60 calories

Basu R, Shah P, Basu A et al (2008) Comparison of the effects of pioglitazone and metformin on hepatic and extra-hepatic insulin action in people with type 2 diabetes