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The beneficial effect of TZT in T2DM and obesity is related to direct activation of GIP and GLP-1 receptors with subsequent improvement of insulin sensitivity and reduction of body weight

Summary Retatrutide, a triple agonist now in phase 3 trials, has the potential to become the most effective pharmacological treatment for obesity while also offering substantial benefits in T2D management and other cardiometabolic risk factors.

When combined with a balanced diet and exercise, it helps reduce fat, lower BMI, and combat visceral fat to support weight management effectively

Learn about how metformin and Ozempic work, what their side effects are, and how much weight you may lose while using these drugs.