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Other studies find no significant benefits

However, these studies did not compare cohorts matched for age and BMI and, consequently, this could represent a chance association (37)

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Of the two main incretin hormones released with food ingestion, the actions of glucagon-like peptide-1 (GLP-1) have been exploited for therapeutic benefit

By contrast, RNA sequencing of normal and ischemic hearts from humans has identified GLP1R mRNA transcripts predominantly in a subset of atrial and ventricular cardiomyocytes, and they are relatively more abundant in human ventricles than in mice (McLean et al