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The case series in Medicine specifically highlighted this mechanism, noting that the body water loss associated with GLP-1 agonists may be more significant than commonly appreciated
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doi: 10.1007/s00125-020-05269-3 21 NashineSKenneyMC
( Epub 2013/05/04 )
That does not prove Retatrutide destroys muscle, but it is another reason not to invent a muscle preserving claim where no athlete trial exists
