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Nonetheless, investigators from the Canadian Network for Observational Drug Effect Studies (CNODES) reported contradictory results

Specifically, compared with DPP-4is, OW GLP-1 RAs were associated with 23% and 13% fewer ASCVD-related hospitalizations and outpatient visits, respectively

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Dose Range: 4 mg/day is the documented trial dose

Differential indication for SGLT-2 inhibitors versus GLP-1 receptor agonists in patients with established atherosclerotic heart disease or at risk for congestive heart failure