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Mechanism of action Ozempic binds to and activates the GLP-1 receptor, leading to a series of physiological effects

Tirzepatide has been associated with improvements in lipoprotein profiles, blood pressure, and inflammation, although favorable effects on cardiovascular risk factors have been reported in only a single clinical trial (Wilson et al., 2020

The multi-dose pen delivers doses of 0.6 mg, 1.2 mg, or 1.8 mg

In this Review, we highlight current understanding of the direct and indirect antiinflammatory effects and mechanisms of GLP-1 medicines in both preclinical and clinical studies, covering emerging concepts, clinical relevance, and areas of uncertainty that require further investigation

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