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International precedent from other patent expiration events suggests that meaningful price reductions typically occur within 12-18 months of the first generic approval, particularly when multiple manufacturers compete simultaneously
Similarly, liraglutide and semaglutide were approved in the United States as anti-obesity medications in 2014 and 2021, respectively
Figure 13: Photograph of nurses administering insulin shock therapy in Lngbro Hospital, Stockholm, in 1930, credit: Wikipedia
Logistics: What does your insurance plan actually cover, and what is your out-of-pocket budget
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