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Torres Fernandez ED, Huffman AM, Syed M, Romero DG, Yanes Cardozo LL

Semaglutide does not treat fibromyalgia pain or underlying fibromyalgia pathology

Currently, available treatments only alleviate symptoms without halting or delaying disease progression

-cell apoptosis is mediated by a series of cascade mechanisms of the cysteine protease family, and current studies on hyperglycemia-induced -cell apoptosis have focused on the balance between the pro-apoptotic Bcl-2 proteins (Bad, Bid, Bik, and Bax) and the anti-apoptotic Bcl family (Bcl-2 and Bcl-xl) (Tomita, 2016), and apoptosis occurs only when the concentration of the pro-apoptotic protein Bcl-2 on the mitochondrial membrane of the intrinsic pathway exceeds the concentration of the anti-apoptotic protein