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It impairs liver function, which affects glucose metabolism

[DOI] [PMC free article] [PubMed] [Google Scholar] 137.Myers MG

The main differences between the two peptides are the following: Development and Approval: Semaglutide was developed later (2010) than liraglutide, and it also received FDA approval much more recently for type 2 diabetes treatment (2017), cardiovascular risk reduction in diabetes (2021) and overweight and obesity management in adults (2021) and adolescents (2023)

The key difference is that without medication, you must rely entirely on willpower, environmental cues, and behavioral patternswhich is significantly harder for people with genetic predispositions toward higher appetite sensitivity

Patients currently using any GLP 1 medication should consult their healthcare provider before making changes as switching between products requires careful dose conversion and monitoring