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This distinction defines what microdosing can and cannot reasonably be expected to accomplish

Serious kidney problems from GLP-1 therapy are rare, but vomiting, diarrhea, and dehydration may impair kidney function in the short term

[DOI] [PubMed] [Google Scholar] 61

13 No RCTs have primarily tested the effects of GLP-1 RAs on HF hard outcomes and/or mortality in patients with HFpEF or HF with reduced ejection fraction (HFrEF)

Additionally, ongoing studies suggest that GLP-1 medications may benefit conditions such as non-alcoholic fatty liver disease (NAFLD) and polycystic ovary syndrome (PCOS) by improving insulin sensitivity, reducing inflammation, and positively influencing metabolism