soul trial oral semaglutide cardiovascular outcomes 2024 results nejm Reduces CV Events in T2DM – (NEJM, Mar 2025) Relevant for: cardiology, diabetology, nephrology, internal medicine 🧪 T2DM + ASCVD/CKD 💊 Oral semaglutide 14 mg vs placebo 📉 Long-term kidney outcomes of semaglutide

Safety Considerations and Side Effects GLP-1 agonists are generally well-tolerated, with common side effects including nausea, vomiting, and diarrhea, especially during the initial stages of treatment

Clinical efficacy depends on the semaglutide molecule itself, not the brand name

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While Semaglutide's primary use is for managing diabetes, it has been found to have significant effects on weight loss

[DOI] [PubMed] [Google Scholar] 80.Parkman HP, Harris AD, Miller MA, et al