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However, there may be subtle differences in their potency and duration of action, which could account for some of the observed differences in effectiveness between the two drugs

Routine Audits: All medication should be checked for valid expiration dating during medication pass
Variants in the FTO gene (rs9939609), GLP1R gene (rs6923761), GIPR gene (rs1800437), and MC4R gene (rs17782313) influence appetite regulation, energy expenditure, and metabolic response to GLP-1 therapy

Future studies should prioritize early PsA populations, ideally using stratified designs that incorporate metabolic profiling, to fully elucidate the dual immunomodulatory and metabolic potential of GLP-1RAs in altering disease trajectory
