is glp 1 venom Gila monster venom… and weight loss? 🦎 It sounds wild, but it's true. GLP-1 medications were inspired by a hormone first discovered in the saliva of a Gila monster. On this week's How a Gila Monster's Venom

But as of today, Glucagon-Like peptide 1 receptor agonists (GLP1-RAs), sodium-glucose cotransporter 2 inhibitors (SGLT2is), dipeptidyl peptidase 4 inhibitors (DPP4is) and mineralocorticoid receptor antagonists, are quickly becoming part of, if not the drugs of choice for diabetes, especially in cases with heart, kidney or liver comorbidities [9,10,11,12]

Inhibition of miR-21 alleviated cardiac perivascular fibrosis via repressing EndMT in T1DM

2017;9:eaan0972 Ast J, Arvaniti A, Fine N, Nasteska D, Ashford FB, Stamataki Z, et al

Some experts believe that cerebral IR is the result of ceramide accumulation in brain tissue, and ROS overproduction occurs due to metabolic abnormalities accompanying peripheral IR and impaired mitochondrial activity in the IR brain.13 Studies have shown that ROS can cause age-related synaptic loss and ultimately cognitive impairment,42 where ROS interactions with inflammation may play a role

Energy metabolism and endocrinology studies: Explored for regulation of systemic energy balance, hormonal pathways, and metabolic processes