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Importantly, initiation of GLP-1RA may decrease levothyroxine dose requirements in patients with hypothyroidism through weight loss, enhance levothyroxine absorption due to delayed gastrointestinal (GI) transit, and have direct effects on the hypothalamic-pituitary-thyroid axis [2329], potentially increasing the risk of thyroid hormone over-replacement (i.e., iatrogenic hyperthyroidism)

Pick the Right Fibre When stomach emptying is already running at tortoise speed, the type of fibre you eat matters a lot

Nature 2020;577:4326.PubMed 47

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