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This observation may be due to inclusion of younger patients with more severe degree of obesity at baseline, and longer follow-up in the obesity trial compared with the diabetes trial (Table 1)

It examines the behavioral and emotional implications, explains how these drugs impact the brain and body, and offers practical, evidence-based strategies for navigating the post-medication phase with confidence

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An iterative process was used, where thin plate regression splines and/or interactions between variables were added until balance was achieved

In addition, we analyze whether the pre-treatment gut microbiome can predict the treatment efficacy