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Because of this and other challenges, employers arent seeing a significant return on their investment or improvements in their employees health. Part of the reason for this low adherence may be attributed to the fact that it can take several months for individuals to work up to the full, effective dose and that some may experience uncomfortable side effects, such as nausea, diarrhea, constipation, vomiting and other gastrointestinal issues contributing to the 10% increase in ER visits that were seen among members after starting a GLP-1

Having backup plans does not guarantee uninterrupted treatment, but it reduces the likelihood that common, solvable problems will force a break

Any medicines prescribed should be MHRA-approved

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reflects their utility and demand, and there are early indications that they could be effective in other therapeutic areas
