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Direct GLP-1 receptor effects on genital tract tissues: limited support for a direct vaginal target Mechanistic caution is warranted because direct GLP-1 receptor expression in vaginal tissue appears low by large transcriptomic resources

It works or you get your money back

The medication slows stomach emptying so dramatically at high doses that food sits in the stomach longer, intensifying queasiness and potentially causing dehydration from fluid loss

However, if your appetite remains largely unchanged during the first seven days, there is no need to panic

Semaglutide has been studied in trials lasting 68 weeks and longer