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doi: 10.1016/j.anaerobe.2019.102135 84 MagneF.GottelandM.GauthierL.ZazuetaA.PesoaS.NavarreteP.et al

In gastric L-cells, the bioactive forms of GLP-1, GLP 737 (glycine-extended GLP-1), and GLP 737 amide , are cleaved from its precursor (pre)proglucagon by prohormone convertase (PC)1 and PC3, which co-generates GLP-2 and oxyntomodulin

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Environmental variables such as temperature, pH, and ionic strength must remain consistent across experimental runs, as these factors can influence peptide stability and interaction behavior

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