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Data from other groups and our recent study have shown that endothelium and cardiac and vascular myocytes express a functional GLP-1R, and participate in the protective cardiovascular effects of GLP-1 analogues 11,36,37,38
Ibuprofen (200400 mg every 68 hours with food, maximum 1.2 g daily for over-the-counter use) may be used if paracetamol proves insufficient, provided you have no contraindications such as kidney disease, cardiovascular conditions, gastric ulcer history, or pregnancy (especially after 20 weeks)

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