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Previous antiobesity medications showed modest efficacy with limited long-term safety data and limited benefits beyond weight loss
Conte, C., Hall, K

GLP-1RAs in type 2 diabetes: mechanisms that underlie cardiovascular effects and overview of cardiovascular outcome data

At approximately $350 per month ($4,200 per year), which reflects typical injectable maintenance dosing, an individual starting at 240 pounds would lose about 36 pounds over 12 months, translating to roughly $116.67 per pound lost

Notably, more than 80% of those who used to take a treatment were only on a therapy for 12 months or less