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Many insurers also have a rule requiring you to try Wegovy or Saxenda first before they approve Zepbound

Hypoglycemia can occur, particularly when tirzepatide is used in combination with insulin or sulfonylureas, though it is uncommon when used as monotherapy due to the glucose-dependent mechanism of insulin secretion

Tirzepatide takes it a step further by also targeting GIP receptors, offering a dual action that provides even greater metabolic benefits
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