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BioWorld - Saturday, July 18, 2026 Breaking News: Best of BioWorld Science: Q2See today's BioWorld Science Home Structural insights into small-molecule GLP-1 agonists To read the full story, subscribe or sign in

Given that a significant portion of generic drugs and their active ingredients are sourced internationally, tariffs will also have the ability to strain supply chains and increase costs for consumers. In this article, we'll review the effect of tariffs on the medications commonly used by members of the Paloma Health patient community

Contact your healthcare provider within 24 hours if you experience: Persistent vomiting (more than 24 hours) preventing adequate fluid intake Severe diarrhea (more than 6 episodes daily) lasting beyond 48 hours Inability to keep down fluids despite anti-nausea measures Weight loss exceeding 23 pounds in 24 hours (likely fluid loss) Markedly reduced urine output with dark, concentrated urine New or worsening dizziness affecting daily activities or causing falls Blood glucose readings consistently above target despite usual management Seek immediate medical attention (emergency department or call 911) for: Severe, persistent abdominal pain (may indicate pancreatitis or gallbladder disease, which are labeled risks of GLP-1 medications requiring immediate evaluation and drug discontinuation) [1] Severe dizziness or fainting episodes Rapid or irregular heartbeat with chest discomfort Confusion, disorientation, or altered mental status Inability to urinate for 12+ hours Signs of acute kidney injury (decreased urine output, swelling, severe fatigue) Symptoms of hyperglycemic emergencies in diabetes patients (excessive thirst, frequent urination, fatigue, fruity breath) Patients with pre-existing kidney disease, heart failure, or those taking multiple medications affecting fluid balance should maintain closer communication with their healthcare team

All beta cell Gipr -knockout mice were bred in-house as previously described 10

The study demonstrated that oral semaglutide was associated with a lower risk of major adverse cardiovascular events (a composite of death from cardiovascular causes, nonfatal myocardial infarction or nonfatal stroke