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There were no cases of vomiting and no treatment discontinuations because of gastrointestinal issues, even among participants receiving the maximum effective dose
Key Pharmacokinetic Parameters The table below describes the key pharmacokinetic parameters for DPP-4 inhibitors: Cautions and contraindications Cautions and contraindications for the use of DPP-4 inhibitors are listed below: Adverse effects Other adverse effects include: Increased risk of infection with saxagliptin, alogliptin and vildagliptin Hypersensitivity reactions (including anaphylaxis, angioedema, stevens-johnson syndrome) Sitagliptin: interstitial lung disease, impaired renal function, thrombocytopenia, and acute renal failure

In contrast, SGLT2 inhibitors should be withheld (typically at least one day preoperatively) to minimize the risk of euglycemic diabetic ketoacidosis
