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Since 2017, Ro has helped millions of patients in nearly every single county in the United States, including 98% of primary care deserts

So allow me to reword this
This system enabled painless transdermal delivery with marked accumulation in arthritic joints, which effectively inhibited chondrocyte ferroptosis via the aforementioned mechanism and also promoted macrophage M2 polarization, thereby attenuating RA progression
Some have to hold the current dose longer or reduce it for a while

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