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Development of a methodology for and assessment of pulsatile luteinizing hormone secretion in juvenile and adult male mice

Following 1:1 propensity score matching, both the GLP-1 RA user and non-user groups included 183,264 patients

doi: 10.1074/jbc.270.44.26488

Most are given by injection, but there is one pill option (Rybelsus)

The cardiovascular benefits observed with these medications include: Reduction in non-fatal myocardial infarction and stroke Decreased cardiovascular mortality in high-risk populations (demonstrated with liraglutide) Improvements in blood pressure and lipid profiles Weight reduction , which independently lowers cardiovascular risk It is important to distinguish between arterial thrombotic events (such as heart attacks and strokes, which some GLP-1 agonists help prevent) and venous thromboembolism (DVT and PE)