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CD86 is a costimulatory ligand expressed mainly by monocytes/macrophages

## Dose Calculation Reference (10mg/ml) | Desired Dose | Volume to Draw | Insulin Syringe Units | |-------------|----------------|----------------------| | 1mg | 0.10ml | 10 units | | 2mg | 0.20ml | 20 units | | 4mg | 0.40ml | 40 units | | 8mg | 0.80ml | 80 units | | 12mg | 1.20ml | Split: 0.60ml x 2 | **Formula:** Dose (mg) / Concentration (mg/ml) = Volume (ml) For doses requiring more than 1ml, split into two injection sites administered the same day

Analysis of efficacy and safety of dulaglutide 0.75 mg stratified by sex in patients with type 2 diabetes in 2 randomized, controlled phase 3 studies in Japan

Saxenda is given as a subcutaneous injection once daily, under the skin of the stomach, thigh, or upper arm