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Metformin and GLP-1 medications are often mentioned together, but they work very differently

(B) Exogenously administered GLP-1, as the one contained in NAOMs, is readily available in systemic circulation, bypassing portal circulation and the deleterious effects of DPP-4

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Evidence is emerging that glucagon-like peptide-1 (GLP-1) receptor agonists have anti-inflammatory and chondroprotective properties independent of their effects on weight loss