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Beyond these established classes, novel agents such as dual and triple receptor agonists are currently being investigated

Cryo-EM structure of the retatrutide-bound human GLP-1R-Gs complex

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The evidence is still preliminary, and more robust trials are needed to confirm the association, says review co-author Pratibha Natesh, an endocrinologist at Warwick Medical School in Coventry, UK.

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