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Description
A novel glucagon-like peptide-1/glucagon receptor dual agonist exhibits weight-lowering and diabetes-protective effects

Clinical data shows tirzepatide produces greater appetite reduction than semaglutide for most people

Tirzepatide 15 mg was also associated with higher incidence of vomiting (OR 5.50 [95% CI 2.40, 12.59], I 2 0%) and diarrhoea (OR 3.31 [95% CI 1.40, 7.85], I 2 52%), while more participants receiving tirzepatide 10 mg experienced vomiting (OR 2.98 [95% CI 1.13, 7.80], I 2 0%) (Table 2)

Novos estimates help bracket the range: Floor (~15%): In early 2025, Novo said ~1M U.S

[DOI] [PMC free article] [PubMed] [Google Scholar] 96.Watchorn D, O'Shea D, Butler MW
