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Study Design and Population Characteristics This retrospective, real-world study extracted data from electronic medical records of an urban pediatric hospital

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Tirzepatide is one of the most popular GLP-1 agonists

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According to the American Diabetes Association Standards of Care, GLP-1 receptor agonists produce weight loss through multiple mechanisms including central appetite regulation and delayed gastric emptying, beyond gastrointestinal side effects alone

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This approach aims to attenuate these responses and leverage a potential metabolic advantage (higher energy expenditure), particularly in insulin-resistant states, while helping to recalibrate the homeostasis of the brains hungersatiety circuits

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