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1 Pharmacological NMDA receptor antagonism dose-dependently lowers body weight but induces hyperthermia

That is a pretty impressive response that you wont get from taking a GLP-1 injectable

Cell Metab 29 , 837843 (2019)

The presence of GLP-1 receptors in the central nervous system, particularly in the ventral tegmental area (VTA) and nucleus accumbens (NAc), suggests their involvement in reward processing and motivation

Figure 5 summarises the 5-year outcomes of interest
