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Shkorfu, W., Fadel, A., Hamsho, M., Ranneh, Y., & Shahbaz, H

Long-term liraglutide ameliorates nigrostriatal impairment via regulating AMPK/PGC-1a signaling in diabetic mice

On average: Semaglutide is associated with about 15 percent body weight loss Liraglutide leads to 5-10 percent weight loss Tirzepatide has resulted in up to 20 percent weight loss in some studies Key points to remember: Research suggests that patients with type 2 diabetes lose on average almost half of the weight loss that is seen for patients without diabetes, in the range of 5-12 percent of their initial weight

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There may be unmeasured confounding factors such as lifestyle, other medications, psychological stress, or health-seeking behavior differences between the groups