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By imitating this function, medications like semaglutide and tirzepatide trick your brain into thinking youre satisfied with smaller meal portions, which helps you maintain a calorie deficit (burning more calories than you consume) to lose weight

explored the beta-cell protective capacity of this increase in alpha-cell GLP-1 production and found that the xenotransplant of PC1/3-expressing alpha-cells into STZ-treated mice improved glucose tolerance and preserved beta-cell mass in a GLP-1R-dependent manner (56)

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You're maintaining the weight you already lost - Hit your goal on standard doses

PMID: 34706925