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This makes them powerful treatments to help women lose weight

In light of this potential significant safety issue, the development of Lotiglipron has been discontinued, meaning the drug did not progress to further clinical trial stages to evaluate its efficacy and safety
95%CI 0.380.98) (Sattar et al., 2021)

"Gastrointestinal tolerability of amylin analogues and GLP-1 receptor agonists: Mechanisms and management strategies." Diabetes, Obesity and Metabolism , 25(8), 2156-2168