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Rapid weight loss from any method, including tirzepatide, can leave excess skin

[DOI] [PubMed] [Google Scholar] 15.Vadini F., Simeone P.G., Boccatonda A., Guagnano M.T., Liani R., Tripaldi R., Di Castelnuovo A., Cipollone F., Consoli A., Santilli F., et al

A., Oboh, G

If you begin GLP-1 therapy, contact your GP promptly if you experience severe abdominal pain (which could indicate pancreatitis), persistent nausea or vomiting, symptoms of thyroid problems (such as a lump in the neck, hoarseness, or difficulty swallowing), or any other concerning symptoms

Why FDA-Approved Dosing Schedules Exist Semaglutide approval by the FDA came after clinical trials testing specific dose escalation protocols over 16-68 weeks
