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Important Note : If you have heart failure, chronic kidney disease, or liver disease, follow your healthcare provider's specific guidance on fluid intake, as these conditions may require fluid restriction rather than increased consumption

However, by matching patients on specific background drug, duration of use of the background drug, and propensity scores generated on the basis of 46 potential confounders, we likely minimised the likelihood of significant confounding

Whereas the GLP-1R has been broadly found across most types of neuronal cells within the brain, spinal cord, and ganglion and peripheral nerve 1,89,91 , with GLP-1 agonsits enhancing neuronal phenotypic markers (e.g., augmenting choline acetyltransferase levels in cholinergic cells and TH levels in DAergic neurons 35,91 ), there is increasing evidence that astrocytes likewise express GLP-1Rs and that injury and neuroinflammation elevate their expression

Where necessary, the state drug controllers are asked to coordinate with the Advertising Standards Council of India (ASCI) and other relevant authorities to ensure effective enforcement

HbA1c Reduction with Tirzepatide vs other anti-diabetic medications (as presented in EASD 2023) Figure 2b