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Polyethylene glycol Loxenatide (PEX-168) The early GLP-1RA takes repeated injections and has a high rate of digestive system side effects, limiting its use

Echocardiographic studies demonstrate that GLP-1 agonists improve global longitudinal strain, an early marker of subclinical diabetic cardiomyopathy, by 1520% [79]

doi: 10.1111/dom.14725 23 MollHFreyEGerberPGeidlBKaufmannMBraunJet al

Virili C, Antonelli A, Santaguida MG, Benvenga S, Centanni M

Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients
