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HR: 0.62, 95% CI: 0.460.84) cannabis use disorder compared to other anti-obesity medications over 12 months, with the largest effects observed in men, Caucasian subjects, and individuals over 55 years of age

Trial participants reported more frequent side effects, such as nausea, vomiting, and gastrointestinal discomfort, with some experiencing more adverse events

For example, in a recent Phase 2 trial, participants lost an average of 15% of their body weight over 12 weeks, a result that exceeds many existing treatments

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