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Moreover, AMPK stimulates the activation of the cAMP/PKA pathway in brown adipocytes, triggering lipolysis through the release of free fatty acids and upregulation of uncoupling protein 1 (UCP1)

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processed cryo-EM data, modeled, refined and analyzed the structure, wrote manuscript with input from all authors

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Verdict at a Glance Tirzepatide is the proven choice with FDA approval and extensive clinical data
