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Evidence from animal studies, nonhuman primate work, and limited early human data suggests that these medications may reduce alcohol consumption, drug cravings, relapse behaviors, and dopamine-driven reward responses

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In contrast, GLP-1RAs@NPs-WYRGRL significantly suppressed the expression of IL-6, cGAS, STING and ACSL4 and enhanced the expression of GLP-1R in chondrocytes induced by LPS compared with the NPs-WYRGRL treatment group (Fig