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Here, we aimed to provide an overview of retatrutide's safety and effectiveness in treating obesity.

Obesity is a chronic disease associated with increased risk of obesity-related complications and mortality

Background: Type 2 diabetes mellitus (T2D) is associated with an increased fracture risk

Methods This is a cohort study combining several population-wide databases and covering a Spanish population of five million inhabitants, including all adults with obesity who initiated treatment with either GLP-1RA or SGLT-2i for type 2 diabetes from 2015 to 2021

Bifidobacterium infantis produces the postbiotic acetate, and interacts with Akkermansia and Butyricum to promote an ecosystem in the gut that naturally boosts GLP-1