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If patients require frequent antidiarrhoeal medication, this suggests the need for medical review and possible treatment adjustment

Dosing adjustments may be needed if either medication has previously caused side effects

It has become widely used due to its ability to help patients lose a significant percentage of body weight while also improving cardiovascular outcomes

Structure-Conformation-Activity Studies of Glucagon and Semi-Synthetic Glucagon Analogs

Because Zepbound is FDA-approved, the SURMOUNT-1 trial result (22.5% mean weight loss with 15mg tirzepatide over 72 weeks) applies to it unlike compounded tirzepatide, which is not FDA-approved and has not been evaluated at that trial scale