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Early non-responders assigned to BT plus AOM achieved a mean percent reduction in randomized body weight of 5.9 0.7% from randomization to week 24
and phase-advances diurnal rhythms of feeding and metabolism into the light cycle, and abolishes the normal increase in dark-cycle locomotor activity [27]
Discuss timing with your prescriber, especially for medications with narrow therapeutic windows
Circulation, 149(17), e1298e1316
