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Results: Under hyperglycemic conditions (11 mM glucose), -cell Ca 2+ was elevated 11031% in NKA1KO islets compared to controls ( P 50% drop in eGFR from baseline with final eGFR 7.0% received add-on therapy: empagliflozin was added for those receiving lobeglitazone, and lobeglitazone was added for those receiving empagliflozin

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[DOI] [PMC free article] [PubMed] [Google Scholar] 650.Nassif ME, Windsor SL, Tang F, et al
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