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Elliott Critical review of the manuscript for important intellectual content: Francesca L

Many patients remain on the 2.5 mg or 5 mg starting doses, which are primarily for tolerability rather than therapeutic effect, and do not reach the 10-15 mg weekly doses where maximal efficacy typically occurs

PlexusDx compounded semaglutide from licensed 503A pharmacies contains the same active molecule as brand Ozempic and works through identical mechanisms

Beck, J

In contrast to GIP, GLP-1 was found to retain its insulinotropic effect in patients, and this fact provides part of the background for the clinical use of GLP-1 receptor agonists in diabetes treatment