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But because Wegovy and similar medicines like Zepbound and Saxenda come at such a high cost, the plan might soon drop coverage as a treatment for weight loss

Diabetologia 36 , 741744 (1993)

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1 Introduction Incretin peptides are secreted from the intestine after nutrient ingestion and enhance glucose-stimulated insulin secretion ( 2 Weight loss pharmacotherapies 2.1 GLP-1R and GIPR agonism reduce body weight in patients with obesity Early GLP-1R agonists were approved to treat T2D ( The mechanism underlying the impressive weight loss potential of GLP-1R agonists is primarily, if not exclusively, mediated by a reduction in energy intake