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Lilly announces $3 billion expansion to injectable drug manufacturing facility for GLP-1 injectables

Clinically, that translates to: More stable post-meal glucose Better appetite regulation Reduced energy crashes Improved satiety Mechanistically: GLP-1 slows gastric emptying, signals fullness centrally, supports insulin secretion, and suppresses glucagon

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After a maximum 12-week screening phase, an anticipated 1840 patients in each trial are randomized (1:1) to semaglutide or placebo for 156 weeks (104-week main treatment phase and 52-week extension)