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METHODS An indirect comparison using the Bucher method 15 was conducted to compare efficacy outcomes of dulaglutide 3.0 and 4.5 mg with semaglutide 1.0 mg using available published results from the SUSTAIN 7 and AWARD11 randomized controlled trials (RCTs)

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A thorough medical evaluation is essential before starting any peptide therapy, including retatrutide

The same Novo Nordisk-funded randomized controlled trial of nearly 2,000 overweight or obese non-diabetic adults also reported their visceral or belly fat was less than at baseline with semaglutide, as was their total fat mass