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Wegovy (semaglutide) was approved by the FDA in 2021

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Because the medication slows stomach emptying, fatty meals sit longer and trigger more pronounced side effects

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Severe Fatigue Despite Normal Glucose: Although fatigue can be a side effect of rapid weight loss or initial GLP-1 therapy, if it persists and is accompanied by other symptoms, it warrants a TSH check to rule out hypothyroid symptoms that might be masked

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Other research has shown increased nasal RNFL [80], choroidal thickness [81] and choroidal folds [72] during HDBR and found that the effect was dose dependent [72, 80]

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Most practitioners begin with comprehensive hormone testing including FSH, LH, estradiol, growth hormone, IGF-1, cortisol, and thyroid hormones to establish baseline values

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