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doi: 10.1016/j.ejim.2017.07.020 12 DruckerD
Briefly, the GLP-1R reporter cells were seeded into white-bottom 96-well assay plates in cell recovery medium (200 L/well) and incubated at 37 C in a humidified atmosphere of 5% CO 2 for 5 h
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Long term data out to 48 weeks did not demonstrate new or alarming risks
The EXSCEL (NCT01144338), HARMONY (NCT02465515), REWIND ( NCT01394952), and AMPLITUDE-O (NCT03496298) trials all demonstrated cardioprotection or near misses for exenatide, albiglutide, dulaglutide and efpeglenatide, respectively
